Prozac (Fluoxetine) Does Not Prevent Relapse of Anorexia Nervosa
Prozac and generic fluoxetine has often been prescribed off-label for treating anorexia nervosa, and a recently JAMA-published in study of 93 discharged anorexic patients (having regained healthy weight) showed that Prozac made no difference in preventing relapse in these patients when compared with a sugar pill.
Antidepressants are often given to discharged anorexic patients to prevent relapse. This study showed that this common prescribing practice provided unsubstantiated benefit for these patients. The study authors suggested that therapy for these patients should focus on psychological and behavioral changes that had shown some modest effectiveness in preventing relapse.
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