I’m glad to hear that the drug Cymbalta has made a difference for you. It does sound like something else or something new has been happening – if you have been isolating yourself for such a long time. Have you spoken with your psychiatrist or psychologist about this?

I would have to defer to your doc about mixing the two – Prozac was listed as one of the meds that docs need to be aware of for patients taking Cymbalta:
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000274

It is in the SNRI class of drugs which means it does have some effect on serotonin reuptake as SSRI class of drugs does, but it also affects norepinephrine (you probably already know this). Any additional drugs that work on serotonin inhibitors need to be carefully monitored if added to another SSRI or SNRI drug.

I would approach this from a more broad angle, looking at biochemical as well as behavioral issues in the symptom you have been experiencing.

Stay strong and ask lots of questions to your doc so you can get the answers you need!
Jane

Currently I am taking 30 mg of Cymbalta. This drug has changed my life in so many ways… I finally smile sometimes. But I still have a major problem. I’ve started locking my self in my room, and its been going on for over a year. I only leave when I have to..or once in a while when I go out.

Are there any drugs to make me want to go out more? I heard alot of good things about Prozac.. but can I mix Prozac with Cymbalta?

I really appreciate your time.. Thanks for all your help.