Dinah at Shrink Rap wrote an article about how she chooses antidepressants for patients who come and see her. The factors, which Dinah’s full article elaborates, include: Past history of response, Family history of response, Patient preference, Other Medical Issues, My Best Guess at What Will Help the Target Symptoms, My Best Guess at the Side Effect Profile, and The Patient’s Financial Concerns and What I have Samples of. Dinah also talks about concerns with weight gain on antidepressants, and how this is often a very individual side effect even if the drug “class” itself has been associated (statistically) with weight gain in patients.